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Dr Matilde Vaghi

Positions held:
  • Reader in Psychology, School of Psychological Sciences
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  • Overview

    Overview

    Biography

    Matilde gained her PhD at the University of Cambridge in 2017 under the supervision of Trevor Robbins (Department of Psychology) and Ed Bullmore (Department of Psychiatry).聽

    Then, she completed a first postdoc at the Max Planck UCL Centre for Computational Psychiatry and Ageing Research and at the Wellcome Centre for Human Neuroimaging in London. Here, Matilde used publicly available datasets from the and worked on understanding the developmental trajectory of cognitive processes and neural networks implicated in psychiatric disorders with Ray Dolan. To enable large-scale and longitudinal data collection, she also contributed to the development of a new smartphone app with Robb Rutledge.聽

    She was awarded a Human Frontier Science Program Fellowship and a to continue her work at Stanford. At Stanford, Matilde worked on neuroimaging approaches to understanding individual brain organisation in patients with psychiatric conditions with Russ Poldrack.聽

    Matilde鈥檚 lab at the聽糖心logo入口, University of London is interested in developing novel approaches to studying brain networks and cognitive processes implicated in psychiatric disorders on the compulsivity spectrum - the aim is to shift the focus from groups to single individuals to move to understanding and personalisation of treatments for people affected by psychiatric disorders.

  • Research

    Research

    Research overview

    The lab works to better understand high cognitive functions and brain mechanisms underlying the emergence, maintenance, and remission of psychiatric conditions. One of the aims is to develop imaging and diagnostic tools to help those who have psychiatric conditions across the lifespan and to translate this knowledge to novel and better-targeted therapeutic interventions. The lab is focused on a within-subject approach, and uses advanced neuroimaging techniques in combination with pharmacology, large-scale based experiments and computational modelling. Together, these modalities allow us to investigate correlates of psychiatric diseases from different, but complementary, angles. We also use resources available through Open Source initiatives. Matilde has been awarded an MRC Career Development Award to start her lab to identify cognitive and neural mechanisms sustaining compulsivity, with individual-level resolution

    We will聽soon聽advertise PhD, Research Assistant and postdoc positions. If you are interested in joining the lab, please email to discuss (m.vaghi@bbk.ac.uk).

    Research Centres and Institutes

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  • Supervision and teaching

    Supervision and teaching

    Supervision

    If you are interested in joining the lab, please email to discuss (m.vaghi@bbk.ac.uk). We have upcoming positions (PostDoc, Research Assistant, PhD) or we may be able to apply for funding together.聽

    Teaching

    I teach in the Module "Structure and Measurement of the Human Brain"

  • Publications

    Publications

    Article

    • Apergis-Schoute, A.M. and van der Flier, F.E. and Ip, S.H.Y. and Kanen, J.W. and Vaghi, Matilde M. and Fineberg, N.A. and Sahakian, B. J. and Cardinal, R.N. and Robbins, T.W. (2024) . Biological Psychiatry Global Open Science 4 (1), pp. 326-335. ISSN 2667-1743.
    • Bedder, R.L. and Vaghi, Matilde M. and Dolan, R.J. and Rutledge, R.B. (2023) . Scientific Reports 13 (1), ISSN 2045-2322.
    • Marzuki, A.A. and Vaghi, Matilde M. and Conway-Morris, A. and Kaser, M. and Sule, A. and Apergis-Schoute, A. and Sahakian, B.J. and Robbins, T.W. (2022) . Journal of Child Psychology and Psychiatry and Allied Disciplines 63 (12), pp. 1591-1601. ISSN 0021-9630.
    • Vaghi, Matilde M. and Hagen, M.P. and Jones, H.M. and Mumford, J. and Bissett, P. and Poldrack, R. (2022) . Translational Psychiatry 12 (271), ISSN 2158-3188.
    • Ersche, K.D. and Lim, T.V. and Murley, A.G. and Rua, C. and Vaghi, Matilde M. and White, T.L. and Williams, G.B. and Robbins, T.W. (2021) . Biological Psychiatry 89 (10), pp. 970-979. ISSN 0006-3223.
    • Gillan, C.M. and Vaghi, Matilde M. and Hezemans, F.H. and Van Ghesel Grothe, S. and Dafflon, J. and Br眉hl, A.B. and Savulich, G. and Robbins, T.W. (2021) . Psychological Medicine 51 (9), pp. 1467-1478. ISSN 0033-2917.
    • Vaghi, Matilde M. and Moutoussis, M. and V谩sa, R.A. and Kievit, R.A. and Hauser, T.U. and Vertes, P.E. and Shahar, N. and Romero-Garcia, R. and Kitzbichler, M.G. and Bullmore, E.T. and NSPN Consortium, None and Dolan, R.J. (2020) . Proceedings of the National Academy of Sciences of the United States of America 117 (41), pp. 25911-25922. ISSN 0027-8424.
    • Romero-Garcia, R. and Seidlitz, J. and Whitaker, K.J. and Morgan, S.E. and Fonagy, P. and Dolan, R.J. and Jones, P.B. and Goodyer, I.M. and Suckling, J. and V茅rtes, P.E. and Bullmore, E.T. and Bullmore, E. and Dolan, R. and Goodyer, I. and Fonagy, P. and Jones, P. and Vaghi, Matilde and Moutoussis, M. and Hauser, T. and Neufeld, S. and Romero-Garcia, R. and St Clair, M. and Whitaker, K. and Inkster, B. and Prabhu, G. and Ooi, C. and Toseeb, U. and Widmer, B. and Bhatti, J. and Villis, L. and Alrumaithi, A. and Birt, S. and Bowler, A. and Cleridou, K. and Dadabhoy, H. and Davies, E. and Firkins, A. and Granville, S. and Harding, E. and Hopkins, A. and Isaacs, D. and King, J. and Kokorikou, D. and Maurice, C. and McIntosh, C. and Memarzia, J. and Mills, H. and O鈥橠onnell, C. and Pantaleone, S. and Scott, J. and Fearon, P. and Suckling, J. and van Harmelen, A.-L. and Kievit, R. and V茅rtes, P. (2020) . Biological Psychiatry 88 (3), pp. 248-259. ISSN 0006-3223.
    • V谩拧a, F. and Romero-Garcia, R. and Kitzbichler, M.G. and Seidlitz, J. and Whitaker, K.J. and Vaghi, Matilde M. and Kundu, P. and Patel, A.X. and Fonagy, P. and Dolan, R.J. and Jones, P.B. and Goodyer, I.M. and V茅rtes, P.E. and Bullmore, E.T. and Bullmore, E. and Dolan, R. and Goodyer, I. and Fonagy, P. and Jones, P. and Moutoussis, M. and Hauser, T. and Neufeld, S. and Romero-Garcia, R. and St Clair, M. and V茅rtes, P. and Whitaker, K. and Inkster, B. and Prabhu, G. and Ooi, C. and Toseeb, U. and Widmer, B. and Bhatti, J. and Villis, L. and Alrumaithi, A. and Birt, S. and Bowler, A. and Cleridou, K. and Dadabhoy, H. and Davies, E. and Firkins, A. and Granville, S. and Harding, E. and Hopkins, A. and Isaacs, D. and King, J. and Kokorikou, D. and Maurice, C. and McIntosh, C. and Memarzia, J. and Mills, H. and O鈥橠onnell, C. and Pantaleone, S. and Scott, J. and Fearon, P. and Suckling, J. and van Harmelen, A.-L. and Kievit, R. (2020) . Proceedings of the National Academy of Sciences of the United States of America 117 (6), pp. 3248-3253. ISSN 0027-8424.
    • Vaghi, Matilde M. and Cardinal, R.N. and Apergis-Schoute, A.M. and Fineberg, N.A. and Sule, A. and Robbins, T.W. (2019) . Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 4 (2), pp. 200-209. ISSN 2451-9022.
    • O'Callaghan, C. and Vaghi, Matilde M. and Brummerloh, B. and Cardinal, R.N. and Robbins, T.W. (2019) . Neuropsychologia 128, pp. 282-289. ISSN 0028-3932.
    • Robbins, T.W. and Vaghi, Matilde M. and Banca, P. (2019) . Neuron 102 (1), pp. 27-47. ISSN 0896-6273.
    • Mihalik, A. and Ferreira, F.S. and Rosa, M.J. and Moutoussis, M. and Ziegler, G. and Monteiro, J.M. and Portugal, L. and Adams, R.A. and Romero-Garcia, R. and V茅rtes, P.E. and Kitzbichler, M.G. and V谩拧a, F. and Vaghi, Matilde M. and Bullmore, E.T. and Fonagy, P. and Goodyer, I.M. and Jones, P.B. and Hauser, T. and Neufeld, S. and St. Clair, M. and Whitaker, K. and Inkster, B. and Prabhu, G. and Ooi, C. and Toseeb, U. and Widmer, B. and Bhatti, J. and Villis, L. and Alrumaithi, A. and Birt, S. and Bowler, A. and Cleridou, K. and Dadabhoy, H. and Davies, E. and Firkins, A. and Granville, S. and Harding, E. and Hopkins, A. and Isaacs, D. and King, J. and Kokorikou, D. and Maurice, C. and McIntosh, C. and Memarzia, J. and Mills, H. and O鈥橠onnell, C. and Pantaleone, S. and Scott, J. and Fearon, P. and Suckling, J. and van Harmelen, A.-L. and Kievit, R. and Dolan, R. and Mour茫o-Miranda, J. (2019) . Scientific Reports 9 (1), ISSN 2045-2322.
    • Fineberg, N.A. and Apergis-Schoute, A.M. and Vaghi, Matilde M. and Banca, P. and Gillan, C.M. and Voon, V. and Chamberlain, S.R. and Cinosi, E. and Reid, J. and Shahper, S. and Bullmore, E.T. and Sahakian, B.J. and Robbins, T.W. (2018) . International Journal of Neuropsychopharmacology 21 (1), pp. 42-58. ISSN 1461-1457.
    • Ghio, M. and Haegert, K. and Vaghi, Matilde M. and Tettamanti, M. (2018) . Philosophical Transactions of the Royal Society B: Biological Sciences 373 (1752), ISSN 0962-8436.
    • Bandelow, B. and Baldwin, D. and Abelli, M. and Bolea-Alamanac, B. and Bourin, M. and Chamberlain, S.R. and Cinosi, E. and Davies, S. and Domschke, K. and Fineberg, N. and Gr眉nblatt, M. and Jarema, M. and Kim, Y.-K. and Maron, E. and Masdrakis, V. and Mikova, O. and Nutt, D. and Pallanti, S. and Pini, S. and Strohle, A. and Thibaut, F. and Vaghi, Matilde M. and Won, E. and Wedekind, D. and Wichniak, A. and Woolley, J. and Zwanzger, P. and Riederer, P. (2017) . World Journal of Biological Psychiatry 18 (3), pp. 162-214. ISSN 1562-2975.
    • Vaghi, Matilde M. and Luyckx, F. and Sule, A. and Fineberg, N.A. and Robbins, T.W. and De Martino, B. (2017) . Neuron 96 (2), pp. 348-354.e4. ISSN 0896-6273.
    • Tettamanti, M. and Vaghi, Matilde M. and Bara, B.G. and Cappa, S.F. and Enrici, I. and Adenzato, M. (2017) . NeuroImage 155, pp. 169-176. ISSN 1053-8119.
    • Vaghi, Matilde M. and Hampshire, A. and Fineberg, N.A. and Kaser, M. and Br眉hl, A.B. and Sahakian, B.J. and Chamberlain, S.R. and Robbins, T.W. (2017) . Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 2 (8), pp. 655-663. ISSN 2451-9022.
    • Vaghi, Matilde M. and V茅rtes, P.E. and Kitzbichler, M.G. and Apergis-Schoute, A.M. and van der Flier, F.E. and Fineberg, N.A. and Sule, A. and Zaman, R. and Voon, V. and Kundu, P. and Bullmore, E.T. and Robbins, T.W. (2017) . Biological Psychiatry 81 (8), pp. 708-717. ISSN 0006-3223.
    • Bandelow, B. and Baldwin, D. and Abelli, M. and Altamura, C. and Dell?Osso, B. and Domschke, K. and Fineberg, N.A. and Gr眉nblatt, E. and Jarema, M. and Maron, E. and Nutt, D. and Pini, S. and Vaghi, Matilde M. and Wichniak, A. and Zai, G. and Riederer, P. (2016) . World Journal of Biological Psychiatry 17 (5), pp. 321-365. ISSN 1562-2975.
    • Ghio, M. and Vaghi, Matilde M. and Perani, D. and Tettamanti, M. (2016) . NeuroImage 132, pp. 93-103. ISSN 1053-8119.
    • Gironi, M. and Saresella, M. and Rovaris, M. and Vaghi, Matilde M. and Nemni, R. and Clerici, M. and Grossi, E. (2013) . Immunity and Ageing 10 (1), ISSN 1742-4933.
    • Ghio, M. and Vaghi, Matilde M. and Tettamanti, M. (2013) . PLoS One 8 (6), ISSN 1932-6203.

    Book section

    • Chamberlain, S.R. and Solly, J.E. and Hook, R.W. and Vaghi, Matilde M. and Robbins, T.W. (2021) . In: Fineberg, N.A. and Robbins, T. (eds.) The Neurobiology and Treatment of OCD: Accelerating Progress. Current Topics in Behavioral Neurosciences. Springer. pp. 125-145. ISBN 9783030753924.
    • Vaghi, Matilde M. (2021) . In: Fineberg, N.A. and Robbins, T.W. (eds.) The Neurobiology and Treatment of OCD: Accelerating Progress. Current Topics in Behavioral Neurosciences. Springer. pp. 97-124. ISBN 9783030753924.

    External Repositories